Updated October 28, 2026

Southern Illinois University School of Medicine acceptance rate

1,218 people applied to Southern Illinois University School of Medicine for fall 2025 and 80 enrolled (AAMC data), so 6.6% of applicants matriculated. The share offered a seat is higher, because some admitted applicants enroll elsewhere.

Applicants enrolled: 6.6%; matriculants per applicant, fall 2025 entry
Applicants: 1,218; fall 2025 entry
Matriculants: 80; fall 2025 entry
MCAT: Not found on the school's site
GPA: Not found on the school's site
Interview format: Two one-on-one faculty interviews

Applicants and matriculants: AAMC FACTS Table A-1, 2025-2026 (matriculants divided by applications, the class that entered in fall 2025). Interview format: SIU School of Medicine: Interview day.

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How the SIU rate is worked out

The AAMC's FACTS Table A-1 lists, for every MD school in the US, how many applications it received and how many students enrolled. For the class that entered in fall 2025, Southern Illinois University School of Medicine received 1,218 applications and enrolled 80 students. 80 divided by 1,218 is 6.6%.

A-1 does not count acceptances by school, so this is not the share of applicants offered a seat. That share is higher, because some admitted applicants choose another school.

In-state and out-of-state applicants

93.1% of applications to SIU came from Illinois residents, and 100.0% of the students who enrolled were Illinois residents. That is about 80 of roughly 1,134 in-state applicants (7.1%) and 0 of roughly 84 out-of-state applicants (0.0%).

Source: AAMC FACTS Table A-1, 2025-2026 (fall 2025 entry). Counts are approximate: they come from A-1's in-state percentages, which are rounded to one decimal.

SIU MCAT and GPA

Southern Illinois University School of Medicine does not list a median or average MCAT or GPA for its entering class on its own website, as far as we could find. We do not estimate these.

What SIU says about its program

Only Illinois residents can apply to SIU's MD program, and out-of-state applicants are considered only for the combined MD/JD. Source
SIU says it is limited to admitting 72 first-year students. Source
When choosing whom to interview, SIU gives preference to central and southern Illinois residents and applicants from rural or inner-city areas. Source

SIU interview format

Two one-on-one faculty interviews. Mode: In person (Springfield campus), video when needed. Structure: 2 interviews: 1 committee member (full file), 1 faculty member (bio and essays). MD/JD: 3.

Sources: SIU School of Medicine: Interview day, SIU School of Medicine: MD admissions, AAMC MSAR 2027 interview report. Checked 2026-10-16.

Full SIU interview guide with practice questions

Questions people ask

What is the SIU medical school acceptance rate?

For the class that started in fall 2025, 1,218 people applied to Southern Illinois University School of Medicine and 80 enrolled, according to AAMC FACTS Table A-1. That is 6.6% of applicants. The AAMC does not publish acceptances by school, so the share offered a seat is somewhat higher, because some admitted applicants choose another school.

What MCAT score do you need for SIU?

Southern Illinois University School of Medicine does not list a median or average MCAT for its entering class on its own website, as far as we could find.

What GPA do you need for SIU?

Southern Illinois University School of Medicine does not list a median or average GPA for its entering class on its own website, as far as we could find.

What is the SIU interview format?

Two one-on-one faculty interviews. Mode: In person (Springfield campus), video when needed. Our SIU interview guide covers the format and practice questions.

Does SIU favor in-state applicants?

About 93.1% of applications came from Illinois residents, and 100.0% of the students who enrolled were Illinois residents (AAMC FACTS Table A-1, 2025-2026). That works out to roughly 7.1% of in-state applicants enrolling, against 0.0% of out-of-state applicants.

Compare similar schools

Confetto is not affiliated with the AAMC or Southern Illinois University School of Medicine. Applicant and matriculant counts are from Table A-1: U.S. MD-Granting Medical School Applications and Matriculants by School, State of Legal Residence, and Gender, Academic Year 2025-2026, © Association of American Medical Colleges, used with attribution. School figures are from SIU's own website, checked 2026-10-28.